Endocrine Abstracts

Aim: Lithium bicarbonate is a drug used in the initial treatment of bipolar disorders. Lithium is an element of alcali metal group and besides being a causative agent for goiter and hypothyroidism primarily, it has also some antithyroid effects. Rarely, lithium may cause hyperthyroidism secondary to thyroiditis or probably autoimmune mechanisms. The association between lithium and thyroid cancer is very little known subject. In this case series, we presented differentiated thy...

Objective: The present study was aimed to investigate the 24 h chronomics of BP/HR in terms of Double amplitude, Acrophase and Hyperbaric index and its relation with circadian rhythm of salivary cortisol in night shift nurses and actual day workers.Material and methods: Fifty-six night shift nurses, aged 20–40 years, performing day and night shift duties were recruited from the Trauma Center, KGMU, India, and 56 age sex matched actual day workers we...

Introduction: Thyroid tumors of uncertain malignant potential (TT-UMP) has been accepted as a subgroup of follicular-patterned thyroid tumors for which benignancy or malignancy cannot be assessed exactly. We aimed to evaluate demographic characteristics, ultrasound (US) findings, and cytological results of patients with TT-UMP and compare these findings with the classical variant of papillary thyroid carcinoma (CV-PTC) and non-encapsulated follicular variant of PTC (NEFV-PTC) ...

Introduction: Hyalinizing trabecular tumor is a very rare neoplasm of thyroid and can be misinterpreted as papillary or medullary cancer in fine needle aspiration biopsy (FNAB).Case report: Multinodular goiter was detected in a 65 years old woman using metformin and L-thyroxine for impaired blood glucose and Hashimoto thyroiditis, respectively. FNAB was performed in two nodules and reported as suspicious for malignancy and benign. She underwent total thy...

Background: Empagliflozin is a sodium-glucose-cotransporter-2 that improves cardiovascular risk and weight loss in patients with type 2 diabetes. Polycystic ovary syndrome (PCOS) is associated with obesity and increased cardiovascular risk; therefore, empagliflozin may be of benefit in PCOS.Methods: A randomised, open-label study in 40 overweight and obese women with PCOS treated with either empagliflozin 25 mg or metformin 1500mg daily for 12 weeks....

Background: Hypothyroidism is one of the most common forms of thyroid dysfunction. And it causes disturbance in electrolyte balance. The increase or decrease in plasma sodium and potassium levels were found to be associated with increase mortality.Objectives: The aimed of the study to measure plasma sodium and potassium levels in Sudanese patients with hypothyroidism.Method: The study is retrospective case control study included 50...

Background: Chronic kidney disease secondary to type 2 diabetes is associated with multifactorial energy dysmetabolism. Irisin has been identified recently as an exercise induced hormone secreted by skeletal muscles. It is hypothesised that patients with CKD may have altered irisin levels.Aim of the work: We aimed to study irisin hormone in type 2 diabetic patient and to assess its relation with diabetic nephropathy (DN).Subjects a...

Introduction: Increasing evidence is available for the role of prolactin in the development of various cancers. The purpose of this study is to evaluate the frequency of thyroid cancer in patients with prolactinoma followed up at a single site.Materials and methods: Medical records of 182 patients, diagnosed with prolactinoma, were reviewed retrospectively. Out of these patients, 114 patients (103 female patients, 11 male patients, mean age 35±10.4)...

Background: Despite available treatment for hypothyroidism, levothyroxine replacement therapy in a biochemically appropriate dose does not necessarily relieve patients’ symptoms and complaints. The aim of the study was to evaluate the concerns of patients treated with hypothyroidism and to correlate these concerns with different patient characteristics and thyroid biochemical control.Method: One hundred and eighteen treated primary hypothyroid patie...

Background: Short synacthen(cosyntropin)test, has replaced the insulin stress test as the first-line test to assess adrenal insufficiency. The aim of this study, was to determine the utility of the 30 and 60 min cortisol measurement in the high dose (250 μg) short synacthen test.Methods: Cross sectional study was conducted by reviewing the database of patients underwent short synacthen test in Al-Faiha Diabetes Endocrine and Metabolism Center (FDEMC...